BDBM178192 US9120808, Example 11::US9120808, Example 12

SMILES CC(=O)OCC=CCC1(N2[C@@H](CC2=O)OC1=CC=O)C(=O)OCc1ccccc1

InChI Key InChIKey=BGQRDDSRQMAZIR-YDJAWIAZSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 178192   

TargetBeta-lactamase(Escherichia coli)
Nabriva Therapeutics

US Patent
LigandPNGBDBM178192(US9120808, Example 11 | US9120808, Example 12)
Affinity DataIC50:  5.32E+5nMpH: 7.0 T: 2°CAssay Description:The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-lactamase TEM(Escherichia coli)
Nabriva Therapeutics

US Patent
LigandPNGBDBM178192(US9120808, Example 11 | US9120808, Example 12)
Affinity DataIC50:  5.90E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-lactamase(Escherichia coli)
Nabriva Therapeutics

US Patent
LigandPNGBDBM178192(US9120808, Example 11 | US9120808, Example 12)
Affinity DataIC50:  2.94E+4nMpH: 7.0 T: 2°CAssay Description:The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-lactamase TEM(Escherichia coli)
Nabriva Therapeutics

US Patent
LigandPNGBDBM178192(US9120808, Example 11 | US9120808, Example 12)
Affinity DataIC50:  7.31E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ...More data for this Ligand-Target Pair
In DepthDetails US Patent