BDBM178423 US9120812, 208

SMILES CCN1CC(C)(C)Oc2nc(nc(-c3ccc(NC(=O)Nc4cc(OC)c(F)cc4F)cc3)c2C1=O)N1CCOC[C@@H]1C

InChI Key InChIKey=PJNZDCOBIISIQD-KRWDZBQOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 178423   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178423(US9120812, 208)
Affinity DataIC50:  1.24E+3nMpH: 7.5Assay Description:The test uses a lucifeurerin/luciferase system to measure the concentration of ATP and its consumption during the enzymatic reaction. The test is per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178423(US9120812, 208)
Affinity DataIC50:  81nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent