BDBM17873 (2S)-2-(2-{3-[(2S)-4-methyl-2-[(4E)-7-methyl-2-(propan-2-yl)oct-4-enamido]pentanamido]-2-oxohexanamido}acetamido)-2-phenylacetic acid::CVS 4819::Ketoamide inhibitor, 1

SMILES CCCC(NC(=O)[C@H](CC(C)C)NC(=O)C(C\C=C\CC(C)C)C(C)C)C(=O)C(=O)NCC(=O)N[C@H](C(O)=O)c1ccccc1

InChI Key InChIKey=KWTWSYDWITXSOY-HWJGHGKNSA-N

Data  1 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17873   

TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM17873((2S)-2-(2-{3-[(2S)-4-methyl-2-[(4E)-7-methyl-2-(pr...)
Affinity DataKi:  4.30E+3nM ΔG°:  -7.44kcal/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair