BDBM179186 US10307413, Compound 249::US10391089, Compound 249::US10980794, Cmpd No 249::US9675614, 249
SMILES O[C@@H](CNC(=O)c1cccc2OCCOc12)CN1CCc2ccccc2C1
InChI Key InChIKey=CIAKAOFNELNPKJ-KRWDZBQOSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 179186
Affinity DataIC50: <100nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Epizyme
US Patent
Epizyme
US Patent
Affinity DataIC50: <100nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair