BDBM17946 (2S,4S,7R)-4-amino-7-(butylcarbamoyl)-5-hydroxy-2,7-dimethylheptyl 1-benzyl-1H-indole-3-carboxylate::Renin nonpeptide inhibitor, 6
SMILES CCCCNC(=O)[C@H](C)CC(O)[C@@H](N)C[C@H](C)COC(=O)c1cn(Cc2ccccc2)c2ccccc12
InChI Key InChIKey=XZLFXZZCYRJLTI-RFIFNAJASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 17946
Affinity DataIC50: 3nMpH: 7.2 T: 2°CAssay Description:In vitro potencies of compounds against purified human recombinant renin were determined by its cleavage of substrate angiotensinogen. The angiotensi...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 2.0 T: 2°CAssay Description:In vitro potencies of compounds against purified porcine pepsin were determined by its cleavage of substrate hemoglobin. After incubation, proteins w...More data for this Ligand-Target Pair