BDBM179638 US9675697, Cpd. No. 319
SMILES COc1cc2c(cc1-c1c(C)noc1C)[nH]c1nc(C)nc(-c3cc(cc(c3)C(C)(C)C)C(=O)NC3CCN(C)CC3)c21
InChI Key InChIKey=XYXCJLYWFUGRHO-UHFFFAOYSA-N
Data 6 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 179638
TargetBromodomain-containing protein 3 [326-398](Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataKi: 1.10nM ΔG°: -12.2kcal/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 2 [91-163](Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataKi: 2.20nM ΔG°: -11.8kcal/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 2 [364-436](Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataKi: 5.20nM ΔG°: -11.3kcal/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 2 [364-436](Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataKi: 5.30nM ΔG°: -11.3kcal/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 3 [51-123](Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataKi: 6.30nM ΔG°: -11.2kcal/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataKi: 9nM ΔG°: -11.0kcal/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair