BDBM179664 US9127001, 6ar::US9127001, 6be::US9127001, 6bf::US9598410, Compound 6bf

SMILES CC(c1ccc(F)cc1)n1nc(c2CN(CCc12)C(C)=O)-c1ccc(F)cc1

InChI Key InChIKey=DBIXCDNXQFZNLL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 179664   

TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM179664(US9127001, 6ar | US9127001, 6be | US9127001, 6bf |...)
Affinity DataIC50:  552nMT: 2°CAssay Description:Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM179664(US9127001, 6ar | US9127001, 6be | US9127001, 6bf |...)
Affinity DataIC50:  500nMT: 2°CAssay Description:Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM179664(US9127001, 6ar | US9127001, 6be | US9127001, 6bf |...)
Affinity DataIC50:  500nMAssay Description:Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliated. Subsequently, TA...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM179664(US9127001, 6ar | US9127001, 6be | US9127001, 6bf |...)
Affinity DataIC50:  552nMAssay Description:Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliated. Subsequently, TA...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM179664(US9127001, 6ar | US9127001, 6be | US9127001, 6bf |...)
Affinity DataIC50:  500nMAssay Description:Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliated. Subsequently, TA...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM179664(US9127001, 6ar | US9127001, 6be | US9127001, 6bf |...)
Affinity DataIC50:  500nMT: 2°CAssay Description:Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...More data for this Ligand-Target Pair
In DepthDetails US Patent