BDBM17982 1,4-benzoxazin-3-one, 19::6-(2,4-diamino-6-ethylpyrimidin-5-yl)-4-(3-methoxypropyl)-2,2-dimethyl-3,4-dihydro-2H-1,4-benzoxazin-3-one

SMILES CCc1nc(N)nc(N)c1-c1ccc2OC(C)(C)C(=O)N(CCCOC)c2c1

InChI Key InChIKey=WPAPODFGOZXFLG-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17982   

TargetRenin(Human)
Pfizer

LigandPNGBDBM17982(1,4-benzoxazin-3-one, 19 | 6-(2,4-diamino-6-ethylp...)
Affinity DataIC50:  90nMpH: 7.4 T: 22°CAssay Description:The renin assay utilized a tandem Green Flourescent Protein (tGFP) substrate that was hydrolyzed by human rennin. The tGFP substrate contained a nine...More data for this Ligand-Target Pair