BDBM179860 US9676701, 94 N-(4′-((trans)-2-aminocyclopropyl)-5-chloro-[1,1′-biphenyl]-3-yl)methanesulfonamide hydrochloride
SMILES CS(=O)(=O)Nc1cc(Cl)cc(c1)-c1ccc(cc1)[C@H]1C[C@@H]1N
InChI Key InChIKey=CQCWLDROOQGZAS-CVEARBPZSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 179860
Affinity DataKi: 50nM ΔG°: -9.95kcal/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Affinity DataKi: 550nMpH: 7.5Assay Description:Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...More data for this Ligand-Target Pair
Affinity DataKi: 550nMpH: 7.5Assay Description:Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...More data for this Ligand-Target Pair