BDBM180366 US9133168, Example 21c::US9133168, Example 22c

SMILES CC1Cc2cc(F)c(F)cc2N1C(=O)Cc1nc(cc(=O)[nH]1)N1CCOCC1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 180366   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM180366(US9133168, Example 21c | US9133168, Example 22c)
Affinity DataIC50:  2nMAssay Description:This test is based on measurement of the expression of AKT protein phosphorylated on serine 473 (P-AKT-S473) in the PC3 human prostate carcinoma line...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM180366(US9133168, Example 21c | US9133168, Example 22c)
Affinity DataIC50:  17nMAssay Description:This test is based on measurement of the expression of AKT protein phosphorylated on serine 473 (P-AKT-S473) in the PC3 human prostate carcinoma line...More data for this Ligand-Target Pair
In DepthDetails US Patent