BDBM18052 3-[({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)methanimidoyl]guanidine::MS-SH08-17::amidinothiouronium, 7

SMILES NC(=N)NC(=N)SCc1cccc(c1)C(F)(F)F

InChI Key InChIKey=DWJNPCRXBNWCJC-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18052   

TargetDihydrofolate reductase(Escherichia coli)
University Of Prince Edward Island

LigandPNGBDBM18052(3-[({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)me...)
Affinity DataIC50:  4.30E+3nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair