BDBM181228 US9139529, 71::US9783501, Compound 71

SMILES Cc1cc(Cl)ccc1Oc1nc2ccccc2cc1C(=O)Nc1cccc(c1)S(N)(=O)=O

InChI Key InChIKey=BJPFKPUSYBFQAD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 181228   

TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM181228(US9139529, 71 | US9783501, Compound 71)
Affinity DataIC50:  14nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM181228(US9139529, 71 | US9783501, Compound 71)
Affinity DataIC50:  14nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In DepthDetails US Patent