BDBM18128 (2S)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]-2-[(1S,3S,4S,5R,8R)-2,4,5,8-tetrahydroxy-7-oxa-2-azabicyclo[3.2.1]octan-3-yl]acetic acid::CHEMBL310012::SB-219383
SMILES [H][C@]1([C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(O)=O)[C@H](O)[C@]2(O)CO[C@@H]([C@@H]2O)N1O
InChI Key InChIKey=JOBDOAKLPNMGKV-OEUXZGCXSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 18128
Affinity DataIC50: 1nMpH: 7.9 T: 2°CAssay Description:The concentration of inhibitor which results in 50% inhibition (IC50) of enzyme activity was determined by preincubating recombinant S. aureus TyrRS ...More data for this Ligand-Target Pair
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibitory activity of compound against tyrosyl tRNA synthetase from mammalian cells was determinedMore data for this Ligand-Target Pair
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibitory activity of compound against tyrosyl tRNA synthetase from Staphylococcus aureus was determinedMore data for this Ligand-Target Pair
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibitory activity against Bacterial Tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair