BDBM181609 US9139577, 4.115::US9708274, 4.115

SMILES COc1cc(cc2ncnc(Nc3ccc(F)cc3O[C@H](C)C(=O)NCC#N)c12)N=S1(=O)CCC1

InChI Key InChIKey=KULZBPBHSDBCPL-CQSZACIVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 181609   

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Evotec International

US Patent
LigandPNGBDBM181609(US9139577, 4.115 | US9708274, 4.115)
Affinity DataIC50:  2nMT: 2°CAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Evotec International

US Patent
LigandPNGBDBM181609(US9139577, 4.115 | US9708274, 4.115)
Affinity DataIC50:  2nMAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent