BDBM182052 US9145391, 1-20

SMILES COC1CC(Cc2ccc(cn2)-c2cc(C)cc(Nc3cc(ccn3)C(F)(F)F)n2)CCC1C(O)=O

InChI Key InChIKey=NMMVNXDLMMHFGV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 182052   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM182052(US9145391, 1-20)
Affinity DataIC50: <0.5nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSyk fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-Syk (Carna Bi...More data for this Ligand-Target Pair
In DepthDetails US Patent