BDBM182053 US9145391, 1-21::US9145391, 1-22

SMILES Cc1cc(Nc2cc(ccn2)C(F)(F)F)nc(c1)-c1ccc(nc1)C1(O)CCCc2cc(ccc12)C(O)=O

InChI Key InChIKey=SBMNBRDVMKTBEU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 182053   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM182053(US9145391, 1-21 | US9145391, 1-22)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSyk fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-Syk (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM182053(US9145391, 1-21 | US9145391, 1-22)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSyk fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-Syk (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent