BDBM18215 (2S)-2-methyl-1-(2,2,2-trifluoroethyl)-9-(trifluoromethyl)-1H,2H,3H,6H,7H-quinolino[7,6-b][1,4]oxazin-7-one::7H-[1,4]Oxazino[3,2-g]quinolin-7-one based compound, (S)-16e

SMILES C[C@H]1COc2cc3[nH]c(=O)cc(c3cc2N1CC(F)(F)F)C(F)(F)F

InChI Key InChIKey=SPBFNRFRJLBCIQ-ZETCQYMHSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 18215   

TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM18215((2S)-2-methyl-1-(2,2,2-trifluoroethyl)-9-(trifluor...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to human Androgen receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM18215((2S)-2-methyl-1-(2,2,2-trifluoroethyl)-9-(trifluor...)
Affinity DataKi:  5.70nM EC50:  3.80nMAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM18215((2S)-2-methyl-1-(2,2,2-trifluoroethyl)-9-(trifluor...)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human Androgen receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed