BDBM182240 US9145391, 12

SMILES Cc1cc(Nc2cc(ccn2)C(F)F)nc(c1)-c1ccc(nc1)C(C)(O)[C@H]1CC[C@@H](CC1)C(O)=O

InChI Key InChIKey=PJSKJVHTCVVYTF-YVZAFYPESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 182240   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM182240(US9145391, 12)
Affinity DataIC50: <0.5nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSyk fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-Syk (Carna Bi...More data for this Ligand-Target Pair
In DepthDetails US Patent