BDBM182862 US9670136, 1 N1-((trans)-2-phenylcyclopropyl)cyclohexane-1,4-diamine::US9670136, 2 (cis)-N1-((1S,2R)-2-phenylcyclopropyl)cyclohexane-1,4-diamine

SMILES NC1CCC(CC1)NC1CC1c1ccccc1

InChI Key InChIKey=ALHBJBCQLJZYON-UHFFFAOYSA-N

Data  6 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 182862   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM182862(US9670136, 1 N1-((trans)-2-phenylcyclopropyl)cyclo...)
Affinity DataKi:  50nM ΔG°:  -9.95kcal/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM182862(US9670136, 1 N1-((trans)-2-phenylcyclopropyl)cyclo...)
Affinity DataKi:  550nM ΔG°:  -8.53kcal/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM182862(US9670136, 1 N1-((trans)-2-phenylcyclopropyl)cyclo...)
Affinity DataKi: >4.00E+4nMAssay Description:Briefly, a fixed amount of MAO (0.25 μg for MAO-A and 0.5 μg for MAO-B) was incubated on ice for 15 minutes in the reaction buffer, in the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM182862(US9670136, 1 N1-((trans)-2-phenylcyclopropyl)cyclo...)
Affinity DataKi: >4.00E+4nMAssay Description:Briefly, a fixed amount of MAO (0.25 μg for MAO-A and 0.5 μg for MAO-B) was incubated on ice for 15 minutes in the reaction buffer, in the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM182862(US9670136, 1 N1-((trans)-2-phenylcyclopropyl)cyclo...)
Affinity DataKi: >4.00E+4nMAssay Description:Briefly, a fixed amount of MAO (0.25 μg for MAO-A and 0.5 μg for MAO-B) was incubated on ice for 15 minutes in the reaction buffer, in the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM182862(US9670136, 1 N1-((trans)-2-phenylcyclopropyl)cyclo...)
Affinity DataKi: >4.00E+4nMAssay Description:Briefly, a fixed amount of MAO (0.25 μg for MAO-A and 0.5 μg for MAO-B) was incubated on ice for 15 minutes in the reaction buffer, in the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM182862(US9670136, 1 N1-((trans)-2-phenylcyclopropyl)cyclo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Briefly, a fixed amount of MAO (0.25 μg for MAO-A and 0.5 μg for MAO-B) was incubated on ice for 15 minutes in the reaction buffer, in the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM182862(US9670136, 1 N1-((trans)-2-phenylcyclopropyl)cyclo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Briefly, a fixed amount of MAO (0.25 μg for MAO-A and 0.5 μg for MAO-B) was incubated on ice for 15 minutes in the reaction buffer, in the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM182862(US9670136, 1 N1-((trans)-2-phenylcyclopropyl)cyclo...)
Affinity DataIC50:  17nMpH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM182862(US9670136, 1 N1-((trans)-2-phenylcyclopropyl)cyclo...)
Affinity DataIC50:  4.42E+4nMAssay Description:Briefly, a fixed amount of MAO (0.25 μg for MAO-A and 0.5 μg for MAO-B) was incubated on ice for 15 minutes in the reaction buffer, in the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM182862(US9670136, 1 N1-((trans)-2-phenylcyclopropyl)cyclo...)
Affinity DataIC50:  135nMpH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM182862(US9670136, 1 N1-((trans)-2-phenylcyclopropyl)cyclo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Briefly, a fixed amount of MAO (0.25 μg for MAO-A and 0.5 μg for MAO-B) was incubated on ice for 15 minutes in the reaction buffer, in the ...More data for this Ligand-Target Pair
In DepthDetails US Patent