BDBM182897 US9676732, 31 6-[2,6-Difluoro-4-(2-phenylethynyl)phenyl]-4H-thiazolo[4,5-d]pyrimidine-5,7-dione

SMILES Fc1cc(cc(F)c1-n1c(=O)[nH]c2ncsc2c1=O)C#Cc1ccccc1

InChI Key InChIKey=VSALCZIQBAVYSB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 182897   

TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM182897(US9676732, 31 6-[2,6-Difluoro-4-(2-phenylethynyl)p...)
Affinity DataEC50:  187nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent