BDBM182900 US9676732, 34 6-[2,6-Difluoro-4-(2-phenylethynyl)phenyl]-1,4-dimethyl-pyrazolo[4,3-d]pyrimidine-5,7-dione

SMILES Cn1ncc2n(C)c(=O)n(-c3c(F)cc(cc3F)C#Cc3ccccc3)c(=O)c12

InChI Key InChIKey=CIIZISUUSIUNFS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 182900   

TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM182900(US9676732, 34 6-[2,6-Difluoro-4-(2-phenylethynyl)p...)
Affinity DataEC50:  74nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent