BDBM182903 US9676732, 37 3-[2,6-Difluoro-4-(2-phenylethynyl)phenyl]-1-isopropyl-pyrido[2,3-d]pyrimidine-2,4-dione

SMILES CC(C)n1c2ncccc2c(=O)n(-c2c(F)cc(cc2F)C#Cc2ccccc2)c1=O

InChI Key InChIKey=ITYCADPBUHMMBM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 182903   

TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM182903(US9676732, 37 3-[2,6-Difluoro-4-(2-phenylethynyl)p...)
Affinity DataEC50:  88nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent