BDBM182904 US9676732, 38 3-[2,6-Difluoro-4-(2-phenylethynyl)phenyl]-1,8-dimethyl-pyrido[3,2-d]pyrimidine-2,4-dione

SMILES Cc1ccnc2c1n(C)c(=O)n(-c1c(F)cc(cc1F)C#Cc1ccccc1)c2=O

InChI Key InChIKey=QMNJGLJZTAVESW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 182904   

TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM182904(US9676732, 38 3-[2,6-Difluoro-4-(2-phenylethynyl)p...)
Affinity DataEC50:  108nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent