BDBM183452 US10214477, Example 51::US9670136, 51 6-amino-N-(4-((trans)-2-((4-aminocyclohexyl)amino)cyclopropyl)-[1,1′-biphenyl]-3-yl)pyridine-3-sulfonamide

SMILES NC1CCC(CC1)NC1C[C@@H]1c1ccc(cc1)-c1cccc(NS(=O)(=O)c2ccc(N)nc2)c1

InChI Key InChIKey=PWPKPNWKBRXCMZ-TXFBUAMLSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 183452   

TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM183452(US10214477, Example 51 | US9670136, 51 6-amino-N-(...)
Affinity DataIC50:  1.00E+5nMAssay Description:Briefly, a fixed amount of MAO (0.25 μg for MAO-A and 0.5 μg for MAO-B) was incubated on ice for 15 minutes in the reaction buffer, in the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM183452(US10214477, Example 51 | US9670136, 51 6-amino-N-(...)
Affinity DataIC50:  1.00E+5nMAssay Description:Briefly, a fixed amount of MAO (0.25 μg for MAO-A and 0.5 μg for MAO-B) was incubated on ice for 15 minutes in the reaction buffer, in the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM183452(US10214477, Example 51 | US9670136, 51 6-amino-N-(...)
Affinity DataIC50:  30nMAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM183452(US10214477, Example 51 | US9670136, 51 6-amino-N-(...)
Affinity DataIC50:  8.78E+6nMAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM183452(US10214477, Example 51 | US9670136, 51 6-amino-N-(...)
Affinity DataIC50:  8.78E+6nMAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM183452(US10214477, Example 51 | US9670136, 51 6-amino-N-(...)
Affinity DataIC50:  30nMpH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent