BDBM183842 US9150526, 95::US9199947, 104

SMILES Cc1cnc(s1)C(CC(O)=O)c1cc(Cl)cc(c1)-c1ccccc1OC(F)(F)F

InChI Key InChIKey=ZAYXQLJKKJFTDJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 183842   

TargetLysosomal protective protein [29-480](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM183842(US9150526, 95 | US9199947, 104)
Affinity DataIC50:  221nMpH: 5.5 T: 2°CAssay Description:The activated cathepsin A was diluted in assay buffer (25 mM MES, pH 5.5, containing 5 mM DTT) and mixed with the test compound (dissolved in assay b...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal protective protein [29-480](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM183842(US9150526, 95 | US9199947, 104)
Affinity DataIC50:  221nMpH: 6.0 T: 2°CAssay Description:Recombinant human cathepsin A (residues 29-480, with a C-terminal 10-His tag; R&D Systems, #1049-SE) was proteolytically activated with recombinant h...More data for this Ligand-Target Pair
In DepthDetails US Patent