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BDBM184171 US9150577, 22

SMILES: CC1CNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1cnn(C)c1

InChI Key: InChIKey=AACPVLDUJNLNFH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 184171   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184171
PNG
(US9150577, 22)
Show SMILES CC1CNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1cnn(C)c1
Show InChI InChI=1S/C17H17N5O2/c1-10-7-18-17(24)15-5-11-3-4-12(6-14(11)22(10)15)16(23)20-13-8-19-21(2)9-13/h3-6,8-10H,7H2,1-2H3,(H,18,24)(H,20,23)
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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

n/an/a 5.10n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair