BindingDB logo
myBDB logout

BDBM184176 US9150577, 28

SMILES: Cc1cc(C)cc(Cn2cc(NC(=O)c3ccc4cc5C(=O)NCCCn5c4c3)cn2)c1

InChI Key: InChIKey=VQJZKKVJRXDIRJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 184176   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184176
PNG
(US9150577, 28)
Show SMILES Cc1cc(C)cc(Cn2cc(NC(=O)c3ccc4cc5C(=O)NCCCn5c4c3)cn2)c1
Show InChI InChI=1S/C25H25N5O2/c1-16-8-17(2)10-18(9-16)14-29-15-21(13-27-29)28-24(31)20-5-4-19-11-23-25(32)26-6-3-7-30(23)22(19)12-20/h4-5,8-13,15H,3,6-7,14H2,1-2H3,(H,26,32)(H,28,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a 1.90n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair