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BDBM184191 US9150577, 44

SMILES: CN1CCN(CC1)c1ccc2[nH]c(NC(=O)c3ccc4cc5C(=O)NCCCn5c4c3)nc2c1

InChI Key: InChIKey=OUMXGZHJISJXIO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 184191   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184191
PNG
(US9150577, 44)
Show SMILES CN1CCN(CC1)c1ccc2[nH]c(NC(=O)c3ccc4cc5C(=O)NCCCn5c4c3)nc2c1
Show InChI InChI=1S/C25H27N7O2/c1-30-9-11-31(12-10-30)18-5-6-19-20(15-18)28-25(27-19)29-23(33)17-4-3-16-13-22-24(34)26-7-2-8-32(22)21(16)14-17/h3-6,13-15H,2,7-12H2,1H3,(H,26,34)(H2,27,28,29,33)
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KEGG

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PC cid
PC sid
UniChem

Similars

n/an/a 2.60n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair