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BDBM184201 US9150577, 57

SMILES: CC1CNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1nc2ccccc2[nH]1

InChI Key: InChIKey=QLEJMZSGBHLAJO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 184201   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184201
PNG
(US9150577, 57)
Show SMILES CC1CNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1nc2ccccc2[nH]1
Show InChI InChI=1S/C20H17N5O2/c1-11-10-21-19(27)17-8-12-6-7-13(9-16(12)25(11)17)18(26)24-20-22-14-4-2-3-5-15(14)23-20/h2-9,11H,10H2,1H3,(H,21,27)(H2,22,23,24,26)
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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

n/an/a 0.590n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair