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BDBM184205 US9150577, 61

SMILES: CC1CNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1nc2ccccc2n1C

InChI Key: InChIKey=UAYPDTAQGNMZQJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 184205   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184205
PNG
(US9150577, 61)
Show SMILES CC1CNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1nc2ccccc2n1C
Show InChI InChI=1S/C21H19N5O2/c1-12-11-22-20(28)18-9-13-7-8-14(10-17(13)26(12)18)19(27)24-21-23-15-5-3-4-6-16(15)25(21)2/h3-10,12H,11H2,1-2H3,(H,22,28)(H,23,24,27)
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KEGG

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PC cid
PC sid
UniChem

Similars

n/an/a 2.20n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair