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BDBM184221 US9150577, 80

SMILES: CCn1c(NC(=O)c2ccc3cc4C(=O)N[C@@H](C)[C@H](C)n4c3c2)nc2ccccc12

InChI Key: InChIKey=UJOPJGOMKOBTAA-KBPBESRZSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 184221   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (Human))
BDBM184221
PNG
(US9150577, 80)
Show SMILES CCn1c(NC(=O)c2ccc3cc4C(=O)N[C@@H](C)[C@H](C)n4c3c2)nc2ccccc12
Show InChI InChI=1S/C23H23N5O2/c1-4-27-18-8-6-5-7-17(18)25-23(27)26-21(29)16-10-9-15-11-20-22(30)24-13(2)14(3)28(20)19(15)12-16/h5-14H,4H2,1-3H3,(H,24,30)(H,25,26,29)/t13-,14-/m0/s1
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Similars

US Patent
n/an/a 5n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair