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BDBM184348 US9150577, 233

SMILES: Cn1cc(NC(=O)c2ccc3cc4C(=O)NCC(C)(C)n4c3c2)nc1C(=O)NC1CCCC1

InChI Key: InChIKey=VMJFJZPFKKPMJU-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 184348   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184348
PNG
(US9150577, 233)
Show SMILES Cn1cc(NC(=O)c2ccc3cc4C(=O)NCC(C)(C)n4c3c2)nc1C(=O)NC1CCCC1
Show InChI InChI=1S/C24H28N6O3/c1-24(2)13-25-22(32)18-10-14-8-9-15(11-17(14)30(18)24)21(31)28-19-12-29(3)20(27-19)23(33)26-16-6-4-5-7-16/h8-12,16H,4-7,13H2,1-3H3,(H,25,32)(H,26,33)(H,28,31)
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KEGG

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PC cid
PC sid
UniChem

Similars

n/an/a 3.70n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair