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BDBM184349 US9150577, 234

SMILES: CC1CCNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1cn(C)c(n1)C(=O)NC1CCCC1

InChI Key: InChIKey=MYNPMSCRXYCTGE-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 184349   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184349
PNG
(US9150577, 234)
Show SMILES CC1CCNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1cn(C)c(n1)C(=O)NC1CCCC1
Show InChI InChI=1S/C24H28N6O3/c1-14-9-10-25-23(32)19-11-15-7-8-16(12-18(15)30(14)19)22(31)28-20-13-29(2)21(27-20)24(33)26-17-5-3-4-6-17/h7-8,11-14,17H,3-6,9-10H2,1-2H3,(H,25,32)(H,26,33)(H,28,31)
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KEGG

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PC cid
PC sid
UniChem

Similars

n/an/a 2.10n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair