BindingDB logo
myBDB logout

BDBM18450 2-({4-[(3-methylphenyl)amino]-6-(morpholin-4-yl)-1,3,5-triazin-2-yl}amino)ethan-1-ol::Triazine compound, 29

SMILES: Cc1cccc(Nc2nc(NCCO)nc(n2)N2CCOCC2)c1

InChI Key: InChIKey=HWSDEDHTXCICDP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18450   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucosylceramidase


(Homo sapiens (Human))
BDBM18450
PNG
(2-({4-[(3-methylphenyl)amino]-6-(morpholin-4-yl)-1...)
Show SMILES Cc1cccc(Nc2nc(NCCO)nc(n2)N2CCOCC2)c1
Show InChI InChI=1S/C16H22N6O2/c1-12-3-2-4-13(11-12)18-15-19-14(17-5-8-23)20-16(21-15)22-6-9-24-10-7-22/h2-4,11,23H,5-10H2,1H3,(H2,17,18,19,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.77E+4n/an/an/an/a5.921



NIH



Assay Description
Enzyme activity was determined as the production of fluorescent resorufin from the substrate. The fluorescence was measured (excitation 570 nm, emiss...


Proc Natl Acad Sci U S A 104: 13192-7 (2007)


Article DOI: 10.1073/pnas.0705637104
BindingDB Entry DOI: 10.7270/Q2V1232M
More data for this
Ligand-Target Pair