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BDBM18451 2-({4-[(4-chlorophenyl)amino]-6-(morpholin-4-yl)-1,3,5-triazin-2-yl}amino)ethan-1-ol::Triazine compound, 30

SMILES: OCCNc1nc(Nc2ccc(Cl)cc2)nc(n1)N1CCOCC1

InChI Key: InChIKey=RLTOZUBSQJGNAU-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18451   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucosylceramidase


(Homo sapiens (Human))
BDBM18451
PNG
(2-({4-[(4-chlorophenyl)amino]-6-(morpholin-4-yl)-1...)
Show SMILES OCCNc1nc(Nc2ccc(Cl)cc2)nc(n1)N1CCOCC1
Show InChI InChI=1S/C15H19ClN6O2/c16-11-1-3-12(4-2-11)18-14-19-13(17-5-8-23)20-15(21-14)22-6-9-24-10-7-22/h1-4,23H,5-10H2,(H2,17,18,19,20,21)
PDB
MMDB

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PC sid
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Similars

Article
PubMed
n/an/a 4.65E+4n/an/an/an/a5.921



NIH



Assay Description
Enzyme activity was determined as the production of fluorescent resorufin from the substrate. The fluorescence was measured (excitation 570 nm, emiss...


Proc Natl Acad Sci U S A 104: 13192-7 (2007)


Article DOI: 10.1073/pnas.0705637104
BindingDB Entry DOI: 10.7270/Q2V1232M
More data for this
Ligand-Target Pair