BDBM185657 US9161922, Table 3, Compound 2

SMILES CCOC(=O)CNC(=O)CNC(=O)C(N)CC#CCN

InChI Key InChIKey=IXWKBWOEDGGEJT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 185657   

TargetMembrane primary amine oxidase(Bos taurus (Bovine))
Case Western Reserve University

US Patent
LigandPNGBDBM185657(US9161922, Table 3, Compound 2)
Affinity DataIC50:  9.00E+4nMpH: 7.2 T: 2°CAssay Description:In the following Examples, 0.9 mL aliquots of a solution of candidate inhibitor in 100 mM potassium phosphate buffer, pH 7.2 was mixed bovine plasma ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase(Komagataella pastoris (Yeast) (Pichia pastoris))
Case Western Reserve University

US Patent
LigandPNGBDBM185657(US9161922, Table 3, Compound 2)
Affinity DataIC50:  3.00E+6nMpH: 7.2 T: 2°CAssay Description:In the following Examples, 0.9 mL aliquots of a solution of candidate inhibitor in 100 mM potassium phosphate buffer, pH 7.2 was mixed bovine plasma ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine oxidase(Arthrobacter globiformis)
Case Western Reserve University

US Patent
LigandPNGBDBM185657(US9161922, Table 3, Compound 2)
Affinity DataIC50:  3.50E+6nMpH: 7.2 T: 2°CAssay Description:In the following Examples, 0.9 mL aliquots of a solution of candidate inhibitor in 100 mM potassium phosphate buffer, pH 7.2 was mixed bovine plasma ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent