BDBM185823 US9163003, 37::USRE46942, Example 37

SMILES COc1ccc(cc1)C(=O)C1CCN(CC1)C1CCN(CC(=O)Nc2nncc3OCCCc23)C1=O

InChI Key InChIKey=JDZOLLKCZDHXOE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 185823   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM185823(US9163003, 37 | USRE46942, Example 37)
Affinity DataIC50:  970nMT: 2°CAssay Description:The human tankyrase 1 PARP catalytic domain, TNKS1P, was cloned into a pDONR221 vector using the Invitrogen Gateway Technology. This entry clone was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM185823(US9163003, 37 | USRE46942, Example 37)
Affinity DataIC50:  3.01E+3nMAssay Description:The human tankyrase 1 PARP catalytic domain, TNKS1P, was cloned into a pDONR221 vector using the Invitrogen Gateway Technology. This entry clone was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM185823(US9163003, 37 | USRE46942, Example 37)
Affinity DataIC50:  970nMAssay Description:The human tankyrase 1 PARP catalytic domain, TNKS1P, was cloned into a pDONR221 vector using the Invitrogen Gateway Technology. This entry clone was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM185823(US9163003, 37 | USRE46942, Example 37)
Affinity DataIC50:  3.01E+3nMT: 2°CAssay Description:The human tankyrase 1 PARP catalytic domain, TNKS1P, was cloned into a pDONR221 vector using the Invitrogen Gateway Technology. This entry clone was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent