BDBM18713 6-(2-methoxyphenyl)-2,2-dimethyl-4-{[(2-phenylethyl)sulfanyl]methyl}-1,2-dihydroquinoline::dihydroquinoline compound, 24::dihydroquinoline-based ligand, 36

SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(CSCCc3ccccc3)c2c1

InChI Key InChIKey=LRGXRETVCQTMNN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 18713   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18713(6-(2-methoxyphenyl)-2,2-dimethyl-4-{[(2-phenylethy...)
Affinity DataIC50:  194nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18713(6-(2-methoxyphenyl)-2,2-dimethyl-4-{[(2-phenylethy...)
Affinity DataIC50: >2.00E+3nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18713(6-(2-methoxyphenyl)-2,2-dimethyl-4-{[(2-phenylethy...)
Affinity DataIC50:  194nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18713(6-(2-methoxyphenyl)-2,2-dimethyl-4-{[(2-phenylethy...)
Affinity DataIC50: >2.00E+3nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed