BDBM18725 6-(2-methoxyphenyl)-2,2-dimethyl-4-[1-(prop-2-en-1-ylsulfanyl)ethyl]-1,2-dihydroquinoline::dihydroquinoline-based ligand, 14

SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(C)SCC=C)c2c1

InChI Key InChIKey=GWXSFBMSMRCBDS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18725   

TargetProgesterone receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18725(6-(2-methoxyphenyl)-2,2-dimethyl-4-[1-(prop-2-en-1...)
Affinity DataIC50:  600nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18725(6-(2-methoxyphenyl)-2,2-dimethyl-4-[1-(prop-2-en-1...)
Affinity DataIC50:  116nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed