BDBM187406 US9169252, 7::US9169252, 8

SMILES CC(C)(O)[C@H](F)CNC(=O)c1cnc(cc1NC1CCCOC1)-n1ccc2cc(cnc12)C#N

InChI Key InChIKey=RCVGDDARVNZGSF-UUSAFJCLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 187406   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM187406(US9169252, 7 | US9169252, 8)
Affinity DataIC50:  1.70nMpH: 7.2Assay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 L prepared from 15 L additions of enzyme and substrates (fluores...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM187406(US9169252, 7 | US9169252, 8)
Affinity DataIC50:  1.60nMpH: 7.2Assay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 L prepared from 15 L additions of enzyme and substrates (fluores...More data for this Ligand-Target Pair
In DepthDetails US Patent