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BDBM187521 US9670191, F16

SMILES: NC(=O)c1cc([nH]c1-c1cccc(F)c1F)-c1ccnc(N)n1

InChI Key: InChIKey=ZRSJFDMHGQGNQC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 187521   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cdc7 Kinase


(Homo sapiens (human))
BDBM187521
PNG
(US9670191, F16)
Show SMILES NC(=O)c1cc([nH]c1-c1cccc(F)c1F)-c1ccnc(N)n1
Show InChI InChI=1S/C15H11F2N5O/c16-9-3-1-2-7(12(9)17)13-8(14(18)23)6-11(21-13)10-4-5-20-15(19)22-10/h1-6,21H,(H2,18,23)(H2,19,20,22)
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PC cid
PC sid
UniChem
US Patent
n/an/a<1.00E+3n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...


US Patent US9670191 (2017)


BindingDB Entry DOI: 10.7270/Q2X63K3K
More data for this
Ligand-Target Pair