BDBM187525 US9670191, F19
SMILES NC(=O)c1cc([nH]c1-c1ccccc1Cl)-c1ccnc(N)n1
InChI Key InChIKey=KRVBJEQIVDIUNS-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 187525
Affinity DataIC50: 615nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences
US Patent
Nerviano Medical Sciences
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair