BindingDB logo
myBDB logout

BDBM187528 US9670191, F21

SMILES: NC(=O)c1cc([nH]c1-c1ccc(Cl)cc1)-c1ccnc(N)n1

InChI Key: InChIKey=ZCYRDJYNBSBJIK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 187528   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cdc7 Kinase


(Homo sapiens (human))
BDBM187528
PNG
(US9670191, F21)
Show SMILES NC(=O)c1cc([nH]c1-c1ccc(Cl)cc1)-c1ccnc(N)n1
Show InChI InChI=1S/C15H12ClN5O/c16-9-3-1-8(2-4-9)13-10(14(17)22)7-12(20-13)11-5-6-19-15(18)21-11/h1-7,20H,(H2,17,22)(H2,18,19,21)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<1.00E+3n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...


US Patent US9670191 (2017)


BindingDB Entry DOI: 10.7270/Q2X63K3K
More data for this
Ligand-Target Pair