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BDBM188269 US9073941, 551

SMILES: COc1ccc2nc(NC(=O)C3CCN(CC3)S(=O)(=O)c3cn(cn3)C(C)C)sc2c1

InChI Key: InChIKey=DPHHUHOEGQBHOK-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 188269   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lipoamide Dehydrogenase (Lpd)


(Mycobacterium tuberculosis)
BDBM188269
PNG
(US9073941, 551)
Show SMILES COc1ccc2nc(NC(=O)C3CCN(CC3)S(=O)(=O)c3cn(cn3)C(C)C)sc2c1
Show InChI InChI=1S/C20H25N5O4S2/c1-13(2)24-11-18(21-12-24)31(27,28)25-8-6-14(7-9-25)19(26)23-20-22-16-5-4-15(29-3)10-17(16)30-20/h4-5,10-14H,6-9H2,1-3H3,(H,22,23,26)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

n/an/a 2.28E+3n/an/an/an/a7.0n/a



Academia Sinica

US Patent


Assay Description
The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...


US Patent US9073941 (2015)


BindingDB Entry DOI: 10.7270/Q2HX1BGC
More data for this
Ligand-Target Pair