BDBM18925 2-{3,5-dichloro-4-[4-hydroxy-3-(3-phenylphenyl)phenoxy]phenyl}acetic acid::4-hydroxy thyromimetic, 9g

SMILES OC(=O)Cc1cc(Cl)c(Oc2ccc(O)c(c2)-c2cccc(c2)-c2ccccc2)c(Cl)c1

InChI Key InChIKey=AQOFZDMQOFEIFY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 18925   

TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM18925(2-{3,5-dichloro-4-[4-hydroxy-3-(3-phenylphenyl)phe...)
Affinity DataIC50:  454nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM18925(2-{3,5-dichloro-4-[4-hydroxy-3-(3-phenylphenyl)phe...)
Affinity DataIC50:  21nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM18925(2-{3,5-dichloro-4-[4-hydroxy-3-(3-phenylphenyl)phe...)
Affinity DataIC50:  20.9nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM18925(2-{3,5-dichloro-4-[4-hydroxy-3-(3-phenylphenyl)phe...)
Affinity DataIC50:  457nMAssay Description:Inhibition of thyroid hormone receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM18925(2-{3,5-dichloro-4-[4-hydroxy-3-(3-phenylphenyl)phe...)
Affinity DataIC50:  20.9nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed