BDBM189336 MAS0 (1)

SMILES Cn1c2nc3N(CC(O)Cn3c2c(=O)n(C)c1=O)c1ccc(O)cc1

InChI Key InChIKey=VYBIIOVQFBOEIL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 189336   

TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
University Of Siena

LigandPNGBDBM189336(MAS0 (1))
Affinity DataIC50:  1.00E+5nMpH: 7.8 T: 2°CAssay Description:HIV RT-associated RNase H activity was measured as previously described.[J. Med. Chem. 2014, 57:3223-3234] Briefly, the reaction mixture comprised ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
University Of Siena

LigandPNGBDBM189336(MAS0 (1))
Affinity DataIC50: >1.00E+5nMpH: 8.1 T: 2°CAssay Description:RNA-dependent DNA polymerase (RDDP) activity was measured as described[J. Microbiol. 2015, 53:288-293] in Tris·HCl buffer (25 mL, 60 mm, pH 8.1) con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed