BDBM19033 1-(3-amino-1,2-benzoxazol-5-yl)-N-[1-(2-{[(2R)-2-hydroxypyrrolidin-1-yl]methyl}phenyl)piperidin-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide::Pyrazole-based inhibitor containing N-arylpiperidiny, 9c
SMILES Nc1noc2ccc(cc12)-n1nc(cc1C(=O)NC1CCN(CC1)c1ccccc1CN1CCC[C@H]1O)C(F)(F)F
InChI Key InChIKey=IYCGPDFYFRTXIV-RUZDIDTESA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 19033
Affinity DataKi: 0.730nM ΔG°: -12.3kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair