BDBM190585 US9181219, 2-{[3-fluoro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-1-(8-methyl-1,2,3,4-tetrahydroquinolin-1-yl)ethan-1-one
SMILES Cc1cccc2CCCN(C(=O)CSc3ncc(cc3F)C(F)(F)F)c12
InChI Key InChIKey=ZSDNADXRHRESKY-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 190585
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Hydra Biosciences
US Patent
Hydra Biosciences
US Patent
Affinity DataIC50: <200nMAssay Description:To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Hydra Biosciences
US Patent
Hydra Biosciences
US Patent
Affinity DataIC50: <200nMAssay Description:Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...More data for this Ligand-Target Pair