BDBM190941 US10077266, Example 53::US9181249, 53::US9708313, 53

SMILES CC(C)Nc1nc2C(C)N(CCc2nc1N1CCC(CC1)Oc1ccc(F)cc1F)C(=O)C(F)F

InChI Key InChIKey=XIOKGNQYBGJUAK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 190941   

TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM190941(US10077266, Example 53 | US9181249, 53 | US9708313...)
Affinity DataIC50:  0.0950nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM190941(US10077266, Example 53 | US9181249, 53 | US9708313...)
Affinity DataIC50:  9.50E+4nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM190941(US10077266, Example 53 | US9181249, 53 | US9708313...)
Affinity DataIC50:  9.50E+4nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
In DepthDetails US Patent