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BDBM190970 US9181249, 83

SMILES: CC(C)Nc1nc2C(C)CN(Cc2nc1N1CCC(CC1)Oc1ccc(F)cc1F)C(=O)N(C)C

InChI Key: InChIKey=YYXWLSPXBILPQX-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 190970   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein coupled receptor 6


(Homo sapiens (Human))
BDBM190970
PNG
(US9181249, 83)
Show SMILES CC(C)Nc1nc2C(C)CN(Cc2nc1N1CCC(CC1)Oc1ccc(F)cc1F)C(=O)N(C)C
Show InChI InChI=1S/C25H34F2N6O2/c1-15(2)28-23-24(29-20-14-33(25(34)31(4)5)13-16(3)22(20)30-23)32-10-8-18(9-11-32)35-21-7-6-17(26)12-19(21)27/h6-7,12,15-16,18H,8-11,13-14H2,1-5H3,(H,28,30)
UniProtKB/SwissProt
UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

Similars

n/an/a 0.0138n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...


US Patent US9181249 (2015)


BindingDB Entry DOI: 10.7270/Q2HM577D
More data for this
Ligand-Target Pair